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While the most extensive Vitamin E studies have been performed on diabetics with higher levels of oxidative stress, researchers have found a link between supplements and increased glutathione levels

Notably, the PtMnIr nanozyme exhibits multiple enzymatic activities, integrating OXD, CAT, SOD, POD, and GPX functionalities, thereby promoting ferroptosis and apoptosis in tumour cells while inhibiting tumour metastasis by establishing an endogenous GSH consumptionROS cyclic generation mechanism [139]

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10.3390/ijms25115906 156 WaetzigV.BelzerM.HaeusgenW.BoehmR.CascorbiI.HerdegenT

Meta-analyses published between 2022 and 2024 consistently report an 1824% elevation in lung cancer incidence among smokers receiving -carotene supplements, a finding corroborated by large-scale trials such as ATBC and CARET (246)